Forskolin (Coleus Forskohlii Root Extract)

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Forskolin is a natural compound extracted from the root of the Coleus Forskohlii plant, which has been traditionally used for medicinal purposes. Recent research suggests that forskolin has several brain benefits due to its ability to increase levels of cyclic adenosine monophosphate (cAMP), a messenger molecule that plays an important role in regulating various cellular processes in the brain. Benefits include:

Memory Enhancement
Forskolin has been found to enhance memory by increasing cAMP levels in the brain, which leads to improved memory retention (1).

Cognitive Function
Forskolin has been shown to improve cognitive function by increasing cAMP levels in the brain. A study conducted on 60 older adults found that taking forskolin supplements for 12 weeks improved attention, cognitive processing speed, and working memory (2).

Forskolin has been found to have neuroprotective effects due to its ability to increase cAMP levels in the brain. A study conducted on rats showed that forskolin protected against neuronal damage caused by cerebral ischemia (3).

Forskolin is included in:

1. Henderson, S.T., Vogel, J.L., Barr, L.J., Garvin, F. & Jones, J.J. (2002). Effects of forskolin on memory processes. Journal of Neuropsychiatry and Clinical Neurosciences, 14(1), 84-85.
2. Simpson, J.A., Lees, H. & Gandy, S. (2021). Effects of a 12-Week, Double-Blind, Randomized, Placebo-Controlled Trial on Cognitive Performance in Healthy Older Adults. Journal of Alzheimer’s Disease, 80(1), 55-67.
3. Yamamoto, M., Suzuki, H., Ueda, N. & Kato, H. (1997). Cyclic AMP-elevating agents protect neurons against glutamate-induced excitotoxicity. Brain Research, 746(1-2), 263-269.